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Over the past few years CoQ10 has gained considerable attention as an agent capable of influencing cellular bioenergetics and counteracting some of the damage caused by free radicals. Animal studies provide increasing support for a beneficial effect of CoQ10 supplements in disease, particularly neurodegenerative diseases and atherosclerosis. These results are encouraging and warrant further investigation, including clinical studies that directly assess a health benefit of CoQ10 supplements in humans.

Consider selenium. In 1996, researchers reported that people who took 200 mcg of selenium a day had a lower risk of prostate, lung, and colon cancer. Until ongoing studies confirm those results, it?s too early to say that selenium prevents cancer. But it?s worth considering a supplement.

Don?t worry about the relatively small amounts of chloride, phosphorus,and potassium in multivitamin supplements. Most people get plenty of chloride from salt, and phosphorus and potassium are best obtained from diets rich in fruits, vegetables, and whole grains..

Niacin (nicotinic acid or nicotinamide) is essential in the form of the coenzymes NAD and NADP in which the nicotinamide moiety acts as electron acceptor or hydrogen donor in many biological redox reactions. NAD functions as an electron carrier for intracellular respiration as well as a codehydrogenase with enzymes involved in the oxidation of fuel molecules. NADP functions as a hydrogen donor in reductive biosyntheses such as in fatty acid and steroid syntheses and, like NAD, as a co-dehydrogenase. NAD, in its only non-redox role, is the substrate for three classes of enzymes that transfer ADP-ribose units to proteins involved in DNA processing, cell differentiation, and cellular calcium mobilization.

The one-a-day vitamin and mineral supplement, introduced in 1940, quickly gained widespread popularity,especially in the United States, where, by 1997, an estimated half of the population was taking a vitamin supplement on a regular basis.